Baroreflex Sensitivity, Blood Pressure and Heart Rate in Children and Adolescents after Anthracycline Treatment for Malignant Tumour
نویسنده
چکیده
The effect of anticancer therapy on cardiovascular regulation was studied in long-term survivors of childhood cancer. Age related changes in systolic (SBP) and diastolic (DBP) blood pressure, mean cardiac interval (CI) and baroreflex sensitivity, expressed in ms/mmHg (BRS) and in Hz/mmHg (BRSf), were monitored after anthracycline treatment. The values found in 20 children treated by anthracycline therapy were compared with those recorded in 16 patients treated with non-anthracycline medication and in 177 healthy subjects. An age-dependent increase in SBP, DBP, CI and a decrease in BRSf were observed in all groups. The age-dependent increase in SBP was decelerated in the children treated with anthracycline.
منابع مشابه
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